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KMID : 0355420090330020321
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Journal of Korean Academy of Oral Health
2009 Volume.33 No. 2 p.321 ~ p.330
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Remineralization effects of combined nano-sized carbonate apatite and fluoride compounds
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Kim Young-Seok
Kwon Ho-Keun
Kim Baek-Il
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Abstract
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Objectives :The aim of this study was to evaluate the remineralization effect on artificial caries-like lesions by combined nano-sized carbonate apatite(n-CAp) and fluoride compounds such as sodium fluoride (NaF) or sodium monofluorophosphate (SMFP).
Methods : The bovine specimens formed artificial caries lesion were assigned to one of the following groups (n = 12): silica 10% dentifrice (control); 1000 ppm NaF dentifrice; 1000 ppm SMFP dentifrice; 1000 ppm NaF+5% n-CAP dentifrice; 1000 ppm SMFP+5% n-CAP dentifrice. The pH-cycling was processed for 14 days. The toothpaste slurries were prepared by mixing 6.7 g of the dentifrice in 13.3 ㎖ of deionized water. In the case of combined n-CAP and fluoride compounds, two components were mixed immediately before treating the specimens. After demineralizing and pH-cycling, the enamel VHN and SEM was again measured. The differences between the baseline or after the treatments (△VHN) were evaluated by ANOVA and a Tukey’s test (a=0.05) for all variables. The analyses were carried out using the SPSS System 12.0 software.
Results :After 14 days of the pH cycling procedure, NaF group had the highest VHN value (150.23±25.52, p<0.05). NaF and SMFP groups combined with n-CAP were less remineralized than NaF-only and SMFP-only groups, repectively. The two groups combined with n-CAP and fluoride groups showed the much higher coverage of calcium fluoride globules than those of only fluoride compounds groups.
Conclusion :The findings of this study indicate that the combination of n-CAP and fluoride compounds had significant effect of calcium fluoride deposition on enamel surface although those combined materials did not significantly affect enamel surface microhardness.
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KEYWORD
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nano-sized carbonate apatite, remineralization, sodium fluoride, sodium monofluorophosphate
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